Patients’ perspectives and perceptions of asthma clinical remission: A global view

<bold>Introduction:</bold> Clinical remission (CR) is an emerging, ambitious treatment goal for asthma patients. Prior survey results suggest the 4-point CR definition is appealing and achievable. As CR evolves with additional criteria, patient perspectives are necessary to understand the value and attainability. <bold>Aims and Objectives:</bold> Explore asthma patient perspectives on the additional criteria and management of CR. <bold>Methods:</bold> An international online community of 125 participants with moderate to severe asthma across 6 countries (France, Germany, Italy, Spain, Japan, USA) were surveyed on CR definitions and management practices using a qualitative-focused survey. CR was defined as OCS freedom, stable/ optimised lung function, symptom control, and no asthma exacerbations over 12 months. Additional criteria included work/school days missed, reduced rescue and maintenance inhaler use, and physician concordance. Response proportions were reported. <bold>Results:</bold> 80% of patients found the additional criteria to be appealing, with 72% rating them as achievable. Parameters beyond symptoms, such as work or school days missed, and reduction of inhaler dose were noted as desirable criteria. Regarding CR management, 67% reported discussing CR and additional criteria at some or most physician appointments; 78% of patients work in partnership with their doctor on their treatment plan, of which 31% report increased patient ownership. <bold>Conclusions:</bold> Patients consider the additional criteria to be appealing and attainable. Elements such as missed work and school days were valued as markers of increased quality of life; 4-point CR and additional criteria are becoming more integrated into patient-physician discussions. <bold>Funding:</bold> GSK (214851)