Relationship between the Severe Asthma Questionnaire and the EQ-5D-5L for health-related quality of life in the SHARP CRC registry
<bold>RATIONALE:</bold> The Severe Asthma Questionnaire (SAQ) provides insight into patients' perceptions of severe asthma. However, policy makers often prefer preference-based measures (PBMs) such as the EuroQol-5D-5L (EQ-5D-5L) to estimate health-related quality of life (HRQoL) for use in economic evaluations. <bold>AIM:</bold> To explore the relationships of the SAQ total and subscales with the EQ-5D-5L index value and dimensions. <bold>Methods:</bold> This study includes real-word data of 222 patients (57% female, mean age 54(SD 14) years, 79% on biologics, mean Asthma Control Questionnaire-6 (ACQ6) score 1.6 (SD 1.3), mean SAQ score 5.1 (SD 1.6) from the Severe Heterogeneous Asthma Research collaboration Patient-centred (SHARP) registry. Relationships between the SAQ total score and subscales (my life, impact on life activities; my mind, emotional impact; my body, impact on extra-pulmonary symptoms and side effects) and the EQ-5D-5L index value and dimensions (UK value set with 5 dimensions: mobility; self-care; usual activities; pain/discomfort; anxiety/depression) were assessed by rank correlation. <bold>Results:</bold> We observed moderate to strong relationships of the SAQ total and subscales with the EQ-5D-5L, especially with the index value and usual activities domain. <bold>CONCLUSION:</bold> The SAQ seems to be a good candidate for mapping to the preference-based EQ-5D-5L for use in economic evaluations. <bold>FUNDING:</bold> SHARP CRC, RAPSODI <fig><object-id>erj;64/suppl_68/PA2159/F1</object-id><object-id>F1</object-id><object-id>F1</object-id><graphic></graphic></fig>
Authors
- Anneke Ten Brinke (ORCID: https://orcid.org/0000-0002-7890-1584)
- Dawn Redwood
- Maria Gonçalves Cunha (ORCID: https://orcid.org/0009-0001-3495-7578)
- Sabina Škrgat (ORCID: https://orcid.org/0000-0002-0136-4733)
- Jacob K. Sont (ORCID: https://orcid.org/0000-0002-5840-0651)
- Matthew Masoli (ORCID: https://orcid.org/0000-0003-0909-0148)
- Simon Doe (ORCID: https://orcid.org/0000-0001-7190-9359)
- M. Elske van den Akker‐van Marle (ORCID: https://orcid.org/0000-0002-5269-509X)
- Inês Farinha (ORCID: https://orcid.org/0000-0002-6161-8547)
- Fleur L. Meulmeester (ORCID: https://orcid.org/0000-0002-8910-9795)
- Kristina Biekšienė (ORCID: https://orcid.org/0009-0008-8933-5283)
- Barbro Dahlén (ORCID: https://orcid.org/0000-0003-3803-9034)
- Jo Tilley
- Pedro Nogueira Costa (ORCID: https://orcid.org/0000-0003-2935-602X)
- L. Havé (ORCID: https://orcid.org/0000-0002-9196-706X)
- Valentyna Yasinska (ORCID: https://orcid.org/0000-0002-1379-1265)
- Joseph Lanario (ORCID: https://orcid.org/0000-0003-0317-9774)
- Jolita Palačionytė (ORCID: https://orcid.org/0009-0003-7329-0504)
- Sanja Hromiš (ORCID: https://orcid.org/0000-0001-6132-1551)
- Peter Kopač (ORCID: https://orcid.org/0000-0001-7261-6689)
- Cláudia Chaves Loureiro (ORCID: https://orcid.org/0000-0003-0438-6126)
- Mariana Paula-Rezelj
- Ana Žaže Bertoncel
- Oksana Tenzelius
- Kathleen Bayani
- Dominique Hamerlynck
- Tania Wainwright
Institutions
- Lithuanian University of Health Sciences (LT)
- University of Exeter (GB)
- Leiden University Medical Center (NL)
- Musgrove Park Hospital (GB)
- Ljubljana University Medical Centre (SI)
- British Lung Foundation (GB)
- Hospitais da Universidade de Coimbra (PT)
- Medisch Centrum Leeuwarden (NL)
- Svenska Örtmedicinska Institute (SE)
- University Clinic of Pulmonary and Allergic Diseases Golnik (SI)
- Newcastle upon Tyne Hospital (GB)
- Swedish Asthma and Allergy Association (SE)
- Hospital Vila Franca de Xira (PT)
- Institute for Pulmonary Diseases of Vojvodina (RS)
- University of Coimbra (PT)
- Newcastle University (GB)
- University of Plymouth (GB)
Publication Details
- Published
- 2024-09-14
- DOI
- https://doi.org/10.1183/13993003.congress-2024.pa2159
- Primary Topic
- Delphi Technique in Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00