Comparing the PUMA and CAPTURE questionnaires for screening for COPD in resource constrained settings

COPD is the 2nd leading cause of death in India but is underdiagnosed, as spirometry is often inaccesible. CAPTURE (COPD Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbation Risk)is a short,5-item questionnaire, and PUMA is a 7-item questionnaire developed to screen patients for symptomatic COPD in primary care. <bold>Aim:</bold>To estimate the accuracy of CAPTURE and PUMA questionnaires for screening for spirometric COPD. <bold>Methods:</bold> Healthy subjects at a health screening were administered the PUMA and CAPTURE questionnaire. COPD was diagnosed if FEV1/FVC ratio <0.7. Score >=2 was abnormal for the CAPTURE and >= 5 for the PUMA questionnaire. Spirometry data were obtained. We analyzed whether the inclusion of a peak expiratory flow rate with a cut-off of 350L/min could improve accuracy. Data were anaylzed using STATA ver 15. <bold>Results:</bold> 355 participants were enrolled. Mean age was 51.5 years, 152(43 %)female. 12 subjects (3.3%) had spirometric COPD. PUMA questionnaire was found to have excellent NPV (97.6%) and specificity (98.2 %). CAPTURE questionnaire had a NPV of 97% and specificity of 87.4%. The NPV improved when combined with a peak expiratory flow rate < 350L/min. <bold>Conclusions:</bold> Both questionnaires perform well to rule out COPD, but had a poor sensitivity. Peak expiratory flow rates in the algorithm might improve the specificity, thereby decreasing the need for spiormetry. <fig><object-id>erj;64/suppl_68/PA2152/F1</object-id><object-id>F1</object-id><object-id>F1</object-id><graphic></graphic></fig>