“He feels his breathing is back to normal”: Diaphragm Position and Patient-Reported Outcomes Following Phrenic Nerve Reconstruction for Diaphragm Paralysis.

<bold>Objective:</bold> To investigate diaphragm position and patient-reported outcomes following phrenic nerve reconstruction for diaphragm paralysis. <bold>Method:</bold> A retrospective chart review was conducted on 50 randomly selected patients with symptomatic diaphragm paralysis who underwent phrenic nerve reconstruction, from a larger cohort of 411 patients treated between 2018 and 2023. The sample size was meticulously chosen to attain 90% power in detecting medium to large effect sizes, with patients selected using systematic random sampling. PROs were obtained from a review of chart notes documenting interactions between the clinical care team and patients. Thoracic radiographic imaging obtained 30 days before and 12 months after surgery were analyzed to assess changes in diaphragm position post-intervention. Diaphragm position was referenced to the nearest rib interspace. <bold>Results:</bold> A paired sample t-test showed a significant depression in diaphragm position postoperatively (M=8.72, SE=.13) compared to baseline measurements (M=7.35, SE=.14), t (37) = -11.66, p<.05, r =.88. Furthermore, a content analysis of chart notes revealed the following PROs: 91% experienced improved respiratory function, 88% reported better sleep quality, and 72% noted increased physical and social functioning. <bold>Conclusion:</bold> The findings endorse phrenic nerve reconstruction as an effective intervention for diaphragm paralysis, showcasing improved diaphragm position and positive PROs. Further research is warranted to address methodological limitations and expand upon these findings.

Authors

Institutions

Publication Details

Published
2024-09-14
DOI
https://doi.org/10.1183/13993003.congress-2024.pa2262
Primary Topic
Congenital Diaphragmatic Hernia Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

“He feels his breathing is back to normal”: Diaphragm Position and Patient-Reported Outcomes Following Phrenic Nerve Reconstruction for Diaphragm Paralysis.

Edward Caruana, Reza Jarrahy, Thomas Bauer, Matthew R. Kaufman et al.
Congenital Diaphragmatic Hernia Studies
article

“He feels his breathing is back to normal”: Diaphragm Position and Patient-Reported Outcomes Following Phrenic Nerve Reconstruction for Diaphragm Paralysis.

Edward Caruana, Reza Jarrahy, Thomas Bauer, Matthew R. Kaufman, Jeannine Sico, Jimmy Naipaul
article en

Abstract

<bold>Objective:</bold> To investigate diaphragm position and patient-reported outcomes following phrenic nerve reconstruction for diaphragm paralysis. <bold>Method:</bold> A retrospective chart review was conducted on 50 randomly selected patients with symptomatic diaphragm paralysis who underwent phrenic nerve reconstruction, from a larger cohort of 411 patients treated between 2018 and 2023. The sample size was meticulously chosen to attain 90% power in detecting medium to large effect sizes, with patients selected using systematic random sampling. PROs were obtained from a review of chart notes documenting interactions between the clinical care team and patients. Thoracic radiographic imaging obtained 30 days before and 12 months after surgery were analyzed to assess changes in diaphragm position post-intervention. Diaphragm position was referenced to the nearest rib interspace. <bold>Results:</bold> A paired sample t-test showed a significant depression in diaphragm position postoperatively (M=8.72, SE=.13) compared to baseline measurements (M=7.35, SE=.14), t (37) = -11.66, p<.05, r =.88. Furthermore, a content analysis of chart notes revealed the following PROs: 91% experienced improved respiratory function, 88% reported better sleep quality, and 72% noted increased physical and social functioning. <bold>Conclusion:</bold> The findings endorse phrenic nerve reconstruction as an effective intervention for diaphragm paralysis, showcasing improved diaphragm position and positive PROs. Further research is warranted to address methodological limitations and expand upon these findings.

University of California, Los Angeles (US), University Hospitals of Leicester NHS Trust (GB), Institute for Advanced Reconstruction (US), Hackensack Meridian Health (US), Chilworth Technology (United Kingdom) (GB)
Openalex Percentile: Top 63%
Congenital Diaphragmatic Hernia Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.