In patients with interstitial lung disease, the greatest drop in oxygen pulse saturation does not occur at the end of the exercise test, but in the minute after

The 1-minute stand-and-sit test (1-STS) has been used to evaluate exercise-induced drop in oxygen pulse saturation (SpO2) in patients with interstitial lung disease (ILD). The behavior of post-exertional SpO2 is not described in the literature, however, in the routine clinical practice of the pulmonary rehabilitation program (PRP) it is considered recorded. In routine practice, it has been observed that in some patients with ILD, SpO2 continues to decrease during the first minute after the end of 1-STS. <bold>Objective:</bold> SpO2 analysis at the end of 1-STS and at the first minute of rest. <bold>Method:</bold> A retrospective analysis of clinical records of PRP patients diagnosed with ILD was performed, comparing the NADIR of SpO2 at the end of the test (NADIR1) and at the first minute of rest (NADIR2). Rad-5® was used in the Massimo SET® pulse oximetry measurement. For statistical analysis, the Wilcoxon test and Spearman's correlation coefficient were used <bold>Results:</bold> A total of 51 tests were analyzed. The age range ranged from 55 to 86 years, with a median age of 75 years, and 55% were women. NADIR1 ranges from 85% to 98% (median 93%) and NADIR2 from 76% to 96% (median: 88%). When evaluating the relationship of the results between NADIR1 and 2, a moderate positive correlation was observed (r: 0.668, p<0.001) and interestingly significant differences were observed between the measurements (p<0.001). <bold>Conclusion:</bold> When comparing both registries, we observed that a deeper desaturation is generated in the recovery, which could describe important clinical implications. This finding suggests different responses to the physiological phenomenon of SpO2.

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Published
2024-09-14
DOI
https://doi.org/10.1183/13993003.congress-2024.pa2607
Primary Topic
Pulmonary Hypertension Research and Treatments
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article
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article

In patients with interstitial lung disease, the greatest drop in oxygen pulse saturation does not occur at the end of the exercise test, but in the minute after

Karina Carrasco, Andrés Pinto Sánchez, Matías Florenzano Váldes, Daniela Diaz Hinojosa et al.
Pulmonary Hypertension Research and Treatments
article

In patients with interstitial lung disease, the greatest drop in oxygen pulse saturation does not occur at the end of the exercise test, but in the minute after

Karina Carrasco, Andrés Pinto Sánchez, Matías Florenzano Váldes, Daniela Diaz Hinojosa, Jennifer Fuentes Landaeta
article en

Abstract

The 1-minute stand-and-sit test (1-STS) has been used to evaluate exercise-induced drop in oxygen pulse saturation (SpO2) in patients with interstitial lung disease (ILD). The behavior of post-exertional SpO2 is not described in the literature, however, in the routine clinical practice of the pulmonary rehabilitation program (PRP) it is considered recorded. In routine practice, it has been observed that in some patients with ILD, SpO2 continues to decrease during the first minute after the end of 1-STS. <bold>Objective:</bold> SpO2 analysis at the end of 1-STS and at the first minute of rest. <bold>Method:</bold> A retrospective analysis of clinical records of PRP patients diagnosed with ILD was performed, comparing the NADIR of SpO2 at the end of the test (NADIR1) and at the first minute of rest (NADIR2). Rad-5® was used in the Massimo SET® pulse oximetry measurement. For statistical analysis, the Wilcoxon test and Spearman's correlation coefficient were used <bold>Results:</bold> A total of 51 tests were analyzed. The age range ranged from 55 to 86 years, with a median age of 75 years, and 55% were women. NADIR1 ranges from 85% to 98% (median 93%) and NADIR2 from 76% to 96% (median: 88%). When evaluating the relationship of the results between NADIR1 and 2, a moderate positive correlation was observed (r: 0.668, p<0.001) and interestingly significant differences were observed between the measurements (p<0.001). <bold>Conclusion:</bold> When comparing both registries, we observed that a deeper desaturation is generated in the recovery, which could describe important clinical implications. This finding suggests different responses to the physiological phenomenon of SpO2.

Universidad de Los Andes, Chile (CL)
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Pulmonary Hypertension Research and Treatments
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