Erythropoiesis disorders in COPD

<bold>Introduction:</bold> Chronic obstructive pulmonary disease (COPD) is now considered a systemic disease. Abnormalities observed in the erythroid lineage are common. Many factors associated with COPD interact with erythropoiesis: smoking, hypoxemia, systemic inflammation, infectious exacerbations. <bold>Methods:</bold> Retrospective study from January 2018 to December 2023, covering 350 patients with COPD collected in the respiratory diseases department of the Ibn Rochd University Hospital in Casablanca. <bold>Results:</bold> Anemia was noted in 18% of patients with COPD. It was microcytic hypochromic in 81% of cases. The average hemoglobin level for these patients was 11 g/dL. Furthermore, polycythemia was noted in 11% of cases. The other associated co-morbidities were dominated by arterial hypertension in 34% of cases, obesity in 9% of cases, diabetes in 6% of cases and dyslipidemia in 21% of cases. All our patients were placed on background treatment. Iron supplementation was recommended in 15% of cases. The outcome was good in 65% of cases and marked by frequent exacerbations in 18% of cases. <bold>Conclusion:</bold> Erythropoiesis disorders associated with COPD are more common in our context. This can be explained by the diagnosis of COPD often at a late stage.

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Published
2024-09-14
DOI
https://doi.org/10.1183/13993003.congress-2024.pa3022
Primary Topic
High Altitude and Hypoxia
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article
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article

Erythropoiesis disorders in COPD

W. Bouddine, N. Zaghba, Hanaa Harraz, Khadija Chaanoun et al.
High Altitude and Hypoxia
article

Erythropoiesis disorders in COPD

W. Bouddine, N. Zaghba, Hanaa Harraz, Khadija Chaanoun, Hanane Benjelloun, Najiba Yassine
article en

Abstract

<bold>Introduction:</bold> Chronic obstructive pulmonary disease (COPD) is now considered a systemic disease. Abnormalities observed in the erythroid lineage are common. Many factors associated with COPD interact with erythropoiesis: smoking, hypoxemia, systemic inflammation, infectious exacerbations. <bold>Methods:</bold> Retrospective study from January 2018 to December 2023, covering 350 patients with COPD collected in the respiratory diseases department of the Ibn Rochd University Hospital in Casablanca. <bold>Results:</bold> Anemia was noted in 18% of patients with COPD. It was microcytic hypochromic in 81% of cases. The average hemoglobin level for these patients was 11 g/dL. Furthermore, polycythemia was noted in 11% of cases. The other associated co-morbidities were dominated by arterial hypertension in 34% of cases, obesity in 9% of cases, diabetes in 6% of cases and dyslipidemia in 21% of cases. All our patients were placed on background treatment. Iron supplementation was recommended in 15% of cases. The outcome was good in 65% of cases and marked by frequent exacerbations in 18% of cases. <bold>Conclusion:</bold> Erythropoiesis disorders associated with COPD are more common in our context. This can be explained by the diagnosis of COPD often at a late stage.

Centre Hospitalier Universitaire Ibn Rochd (MA)
Openalex Percentile: Top 78%
High Altitude and Hypoxia
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Erythropoiesis disorders in COPD — W. Bouddine, N. Zaghba, et al. · (2024) | TGRS Research Map | TGRS