Covid 19 emerging as etiology for novel phenotype of Asthma

<bold>Background:</bold> In India, concerns are rising about "long-COVID" symptoms after surviving COVID-19. Studies suggest a significant portion, especially those with severe infections, develop cough, wheezing, and shortness of breath similar to asthma. We are now entering a post-COVID era in which many postCOVID-19 patients continue to suffer from respiratory symptoms like coughing, dyspnea, or wheezing even after the viral infection has subsided. <bold>Objective:</bold> The Study aims to evaluate the clinical presentation ,lab values along with lung function In Covid 19 affected patients. <bold>Methods:</bold> 140 individuals with a record of COVID-19 pneumonia and asthma like symptoms were enrolled and evaluated in 12 month on basis of clinical presentation, Serum IgE, absolute eosinophil count. PFT parameters like FEV1, FEV25-75 were assessed. <bold>Results:</bold> Patient who had mild Covid 19 pneumonia having oxygen saturation above 95% and not requiring oxygen support comprises of 76(57%), those who needed hospital admission due to oxygen saturation below 90% comprises of 20 (14%) and with moderate covid pneumonia with spo2 between 90-95% include 44(31.4%). Predominant symptoms were cough in 133(95%), followed by wheezing in 120 (85.6%) but breathlessness in 60(42%) only. Spirometry is normal in 86(61.4%), whereas mild obstruction in 20(14.2%) and 34(24.2%) patients had only small airway obstruction. In lab parameters, AEC is below 200 in 113(80.7%) and above 200 only in 27(19.2%) where as Serum IgE(Total) is above 500IU in 18(12.8%), 200-500 in 82(58.5%) and normal range in 40(28.5%). <bold>Conclusion:</bold> Our study suggest that recent COVID-19 infection is leading to new varient of asthma with preserved lung function and peculiar lab values than Asthma which we are aware of.

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Publication Details

Published
2024-09-14
DOI
https://doi.org/10.1183/13993003.congress-2024.pa3940
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
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article

Covid 19 emerging as etiology for novel phenotype of Asthma

Abhisheka Kumar
Inhalation and Respiratory Drug Delivery
article

Covid 19 emerging as etiology for novel phenotype of Asthma

Abhisheka Kumar
article en

Abstract

<bold>Background:</bold> In India, concerns are rising about "long-COVID" symptoms after surviving COVID-19. Studies suggest a significant portion, especially those with severe infections, develop cough, wheezing, and shortness of breath similar to asthma. We are now entering a post-COVID era in which many postCOVID-19 patients continue to suffer from respiratory symptoms like coughing, dyspnea, or wheezing even after the viral infection has subsided. <bold>Objective:</bold> The Study aims to evaluate the clinical presentation ,lab values along with lung function In Covid 19 affected patients. <bold>Methods:</bold> 140 individuals with a record of COVID-19 pneumonia and asthma like symptoms were enrolled and evaluated in 12 month on basis of clinical presentation, Serum IgE, absolute eosinophil count. PFT parameters like FEV1, FEV25-75 were assessed. <bold>Results:</bold> Patient who had mild Covid 19 pneumonia having oxygen saturation above 95% and not requiring oxygen support comprises of 76(57%), those who needed hospital admission due to oxygen saturation below 90% comprises of 20 (14%) and with moderate covid pneumonia with spo2 between 90-95% include 44(31.4%). Predominant symptoms were cough in 133(95%), followed by wheezing in 120 (85.6%) but breathlessness in 60(42%) only. Spirometry is normal in 86(61.4%), whereas mild obstruction in 20(14.2%) and 34(24.2%) patients had only small airway obstruction. In lab parameters, AEC is below 200 in 113(80.7%) and above 200 only in 27(19.2%) where as Serum IgE(Total) is above 500IU in 18(12.8%), 200-500 in 82(58.5%) and normal range in 40(28.5%). <bold>Conclusion:</bold> Our study suggest that recent COVID-19 infection is leading to new varient of asthma with preserved lung function and peculiar lab values than Asthma which we are aware of.

Patna Medical College and Hospital (IN)
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Openalex Percentile: Top 63%
Inhalation and Respiratory Drug Delivery
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Covid 19 emerging as etiology for novel phenotype of Asthma — Abhisheka Kumar · (2024) | TGRS Research Map | TGRS