Evaluation of Bronchiectasis in Children

<bold>Introduction:</bold> It was aimed to evaluate the clinical features of cystic fibrosis(CF) and non-CF bronchiectasis(BE) in children <bold>Method:</bold> Between 2006 and 2023, all patients aged 0-18 years admitted with BE detected on CT were included. Data were retrospectively recorded. BE severity was scored according to the total Bhalla score(TBS) as mild, moderate, or severe. <bold>Results:</bold> 157 patients were included, 51% were female. The most common etiologies were CF, post-infectious, immunodeficiency, primary ciliary dyskinesia, and others. In CF (Group1), patients had lower initial visit age, height, BMI z-score compared to non-CF (Group 2)(p <0.001), whereas no difference was found in final z-scores (p>0.05). There was an increase in final height, weight and BMI z-scores compared to the initial visit in Group 1 (p<0.05). There was no difference in initial and final growth z-scores in Group 2 (p>0.05). In Group 1, the mean age at the first visit was younger and follow-up period was longer (p <0.05). No difference between the groups was found in mean diagnosis age, final visit FEV1, and FVC values. According to the TBS 27.0% of Group 1 were classified as mild, 37.8% moderate, and 35.1% severe, while in Group 2, 61.7% were mild, 33.3% moderate, and 5% severe. Severe scores were more common in Group1 (p <0.001). There was a positive correlation between TBS and initial and final visit height, weight, and BMI z-scores, final FEV1, FVC(p <0.05). <bold>Discussion:</bold> Although severe scores were more common in CF, no difference in final spirometry parameters between CF and non-CF patients suggests that the increase in follow-up height, weight, and BMI z-scores may be due to earlier monitoring and longer follow-up. Spirometry and growth z-scores were associated with radiological scores.

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Published
2024-09-14
DOI
https://doi.org/10.1183/13993003.congress-2024.pa3316
Primary Topic
Cystic Fibrosis Research Advances
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article
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article

Evaluation of Bronchiectasis in Children

Tuğba Şişmanlar Eyüboğlu, Merve Yazol, Ayşe Tana Aslan, Handan Kekeç et al.
Cystic Fibrosis Research Advances
article

Evaluation of Bronchiectasis in Children

Tuğba Şişmanlar Eyüboğlu, Merve Yazol, Ayşe Tana Aslan, Handan Kekeç, Öznur Boyunağa, Volkan Medeni, Yasemin Duman
article en

Abstract

<bold>Introduction:</bold> It was aimed to evaluate the clinical features of cystic fibrosis(CF) and non-CF bronchiectasis(BE) in children <bold>Method:</bold> Between 2006 and 2023, all patients aged 0-18 years admitted with BE detected on CT were included. Data were retrospectively recorded. BE severity was scored according to the total Bhalla score(TBS) as mild, moderate, or severe. <bold>Results:</bold> 157 patients were included, 51% were female. The most common etiologies were CF, post-infectious, immunodeficiency, primary ciliary dyskinesia, and others. In CF (Group1), patients had lower initial visit age, height, BMI z-score compared to non-CF (Group 2)(p <0.001), whereas no difference was found in final z-scores (p>0.05). There was an increase in final height, weight and BMI z-scores compared to the initial visit in Group 1 (p<0.05). There was no difference in initial and final growth z-scores in Group 2 (p>0.05). In Group 1, the mean age at the first visit was younger and follow-up period was longer (p <0.05). No difference between the groups was found in mean diagnosis age, final visit FEV1, and FVC values. According to the TBS 27.0% of Group 1 were classified as mild, 37.8% moderate, and 35.1% severe, while in Group 2, 61.7% were mild, 33.3% moderate, and 5% severe. Severe scores were more common in Group1 (p <0.001). There was a positive correlation between TBS and initial and final visit height, weight, and BMI z-scores, final FEV1, FVC(p <0.05). <bold>Discussion:</bold> Although severe scores were more common in CF, no difference in final spirometry parameters between CF and non-CF patients suggests that the increase in follow-up height, weight, and BMI z-scores may be due to earlier monitoring and longer follow-up. Spirometry and growth z-scores were associated with radiological scores.

Ankara University (TR), Gazi University (TR)
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Cystic Fibrosis Research Advances
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