Demographic and asthma-related characteristics of asthmatics using pressurized metered dose inhalers and dry powder inhalers

<bold>Background:</bold> Asthma controller medications can be delivered via pressurized Metered Dose Inhaler (pMDI) or Dry Powder Inhaler (DPI) devices. <bold>Objective:</bold> This study aimed to evaluate the frequency of exacerbations and satisfaction rate with device use in asthmatics using pMDIs or DPIs. <bold>Methods:</bold> A multicenter, cross-sectional study was conducted in adults who used pMDIs or DPIs for asthma treatment if they complied with their treatments and if they applied treatment with correct inhaler technique. Demographic and asthma-related characteristics of the subjects and data regarding device satisfaction were collected through a face-to-face interview in the outpatient clinic. Rates of pMDI and DPI users and the data were compared between the two groups. <bold>Results:</bold> The study included 338 patients (mean age: 48.6±14.5 years, 253 (74.9%) women). Among participants, 96 (28.4%) were using pMDI and 242 (71.6%) were using DPI. The age of patients using pMDI were significantly lower compared to DPI users. Rate of device satisfaction, number of asthma exacerbations and hospitalizations due to exacerbations were not significantly different between the groups. <bold>Conclusion:</bold> This multicenter study conducted without the support of any pharmaceutical company provides real-life data on asthma patients who comply with treatment and have the correct inhaler technique. More asthmatics use DPIs, however pMDIs are especially preferred in younger asthmatic patients. No significant difference in terms of device satisfaction and clinical outcomes of asthma was observed between pMDI and DPI users.

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Published
2024-09-14
DOI
https://doi.org/10.1183/13993003.congress-2024.pa3916
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
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article

Demographic and asthma-related characteristics of asthmatics using pressurized metered dose inhalers and dry powder inhalers

Kurtuluş Aksu, Yalçın Solak, Ayşe Çoşkun Beyan, Aylin Çapraz et al.
Inhalation and Respiratory Drug Delivery
article

Demographic and asthma-related characteristics of asthmatics using pressurized metered dose inhalers and dry powder inhalers

Kurtuluş Aksu, Yalçın Solak, Ayşe Çoşkun Beyan, Aylin Çapraz, Funda Aksu, Burcu Yormaz, Gürgün Tuğçe Vural Solak, Pınar Mutlu, Levent Cem Mutlu, Ezgi Erdem Türe, Görkem Vayısoğlu Şahin
article en

Abstract

<bold>Background:</bold> Asthma controller medications can be delivered via pressurized Metered Dose Inhaler (pMDI) or Dry Powder Inhaler (DPI) devices. <bold>Objective:</bold> This study aimed to evaluate the frequency of exacerbations and satisfaction rate with device use in asthmatics using pMDIs or DPIs. <bold>Methods:</bold> A multicenter, cross-sectional study was conducted in adults who used pMDIs or DPIs for asthma treatment if they complied with their treatments and if they applied treatment with correct inhaler technique. Demographic and asthma-related characteristics of the subjects and data regarding device satisfaction were collected through a face-to-face interview in the outpatient clinic. Rates of pMDI and DPI users and the data were compared between the two groups. <bold>Results:</bold> The study included 338 patients (mean age: 48.6±14.5 years, 253 (74.9%) women). Among participants, 96 (28.4%) were using pMDI and 242 (71.6%) were using DPI. The age of patients using pMDI were significantly lower compared to DPI users. Rate of device satisfaction, number of asthma exacerbations and hospitalizations due to exacerbations were not significantly different between the groups. <bold>Conclusion:</bold> This multicenter study conducted without the support of any pharmaceutical company provides real-life data on asthma patients who comply with treatment and have the correct inhaler technique. More asthmatics use DPIs, however pMDIs are especially preferred in younger asthmatic patients. No significant difference in terms of device satisfaction and clinical outcomes of asthma was observed between pMDI and DPI users.

Çanakkale Onsekiz Mart Üniversitesi (TR), Tekirdağ Namık Kemal University (TR), Selçuk University (TR), Dokuz Eylül University (TR), Mardin Artuklu University (TR), Directorate of Health (IS), Ankara Atatürk Eğitim ve Araştırma Hastanesi (TR), Memorial Ankara Hospital (TR), Sağlık Bilimleri Üniversitesi (TR), Amasya Üniversitesi (TR)
Openalex Percentile: Top 63%
Inhalation and Respiratory Drug Delivery
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