The adherence in the NEWTON population: a preliminary assessment

<bold>RATIONALE:</bold> Adherence and inhaler issues including inhalation technique and drug deposition are important underlying causes of inadequate asthma control. <bold>OBJECTIVES:</bold> To provide an interim analysis as part of the NEWTON study, the adherence was assessed with a 12-item Test of Adherence to Inhalers’ (TAI-12) after 3 and 6 months from starting the treatment with beclometasone dipropionate/formoterol fumarate (BDP/F) 100/6 µg dry powder inhaler via NEXThaler®. <bold>METHODS:</bold> NEWTON is a multinational (DE, ES, FR, HU, IT, RO), 6-month observational study including, among secondary objectives, the evaluation of adherence in 650 not adequately controlled patients suffering from asthma and receiving extrafine BDP/FF 100/6 µg via NEXThaler®. <bold>RESULTS:</bold> Among the 345 patients considered as evaluable for this analysis, 278 and 205 patients completed the TAI-12 at 3 and 6-month follow-up visits, respectively. The TAI score improves significantly (p>0.0001) from baseline to both 3 and 6 months. The figure shows the level of adherence. <bold>CONCLUSIONS:</bold> These preliminary results show an improvement in the level of adherence after 3 and 6 months of treatment with extrafine BDP/FF 100/6 µg via NEXThaler®. <fig><object-id>erj;64/suppl_68/PA4498/F1</object-id><object-id>F1</object-id><object-id>F1</object-id><graphic></graphic></fig>