Evaluation of postinfectious bronchiolitis obliterans patients in the Childhood Interstitial Lung Diseases Registry of Türkiye

<bold>Introduction:</bold> Despite the great impact of PIBO on children, clinical data is scarce, and most clinicians need more awareness of the disease. We aimed to evaluate patients' demographic, clinical, radiologic findings with PIBO in the Childhood Interstitial Lung Diseases Registry of Türkiye(chILD-TR). <bold>Materials and Methods:</bold> The current age, gender, symptoms, systemic diseases, physical examination, laboratory and radiological findings, therapies of patients with PIBO in the chILD-TR database were recorded in 2022-2023. <bold>Results:</bold> There were 180 patients, 61.1% were male. The current age of the patients was 103.23(13-364), the age at which symptoms started was 25.96(0-233.1), the age at hospital admission was 48.65(0-303.9) months.56.1% of the patients had a history of recurrent lower respiratory tract infection, 17.8% of the patients had growth retardation. The most common symptom was cough(77.8%). Oxygen was used in 12.8% of the patients, noninvasive mechanical ventilator was used in 3.3%. The most common physical examination finding was rhonchi(61.7%). There was a mosaic perfusion pattern in all patients on thorax CT;other common findings were increased aeration(42.8%), thickening of the bronchial wall(41.1%). Mean FEV1, FVC, MEF25-75 values were 61.12±21.68%, 66.45±22.55%, 50.26±28.10%. The most common infection agent was adenovirus(17.2%). 32.2% of patients were using oral steroids. The follow-up period was 85.24±68.29 months. 2 of the patients died. <bold>Discussion:</bold> Physicians need better awareness of PIBO as patients were referred to a pediatric pulmonologist almost 2 years after symptom onset. Patient registries have an essential role in increasing awareness.

Authors

Institutions

Publication Details

Published
2024-09-14
DOI
https://doi.org/10.1183/13993003.congress-2024.pa4956
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Evaluation of postinfectious bronchiolitis obliterans patients in the Childhood Interstitial Lung Diseases Registry of Türkiye

Tuğba Şişmanlar Eyüboğlu, Ebru Yalçın, Saniye Girit, Halime Nayır Büyükşahin et al.
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Evaluation of postinfectious bronchiolitis obliterans patients in the Childhood Interstitial Lung Diseases Registry of Türkiye

Tuğba Şişmanlar Eyüboğlu, Ebru Yalçın, Saniye Girit, Halime Nayır Büyükşahin, Ece Ocak, Figen Gülen, Güzin Cinel, Tuğba Ramaslı Gürsoy, Ahmet Cevdet Ceylan, Ayşe Ayzıt Kılınç, Yasemi̇n Gökdemi̇r, Dıclehan Orhan, Cengiz Korkmaz, Erkan Çakır, Birce Sunman, Aslı İmran Yılmaz, Nural Ki̇per, Abdurrahman Erdem Başaran, Melih Hangül, Şule Selin Akyan Soydaş, Ela Erdem Eralp, Sinem Can Oksay, Mehmet Köse, Bulent Taner Karadag, Ayşen Bingöl, Nazan Çobanoğlu, Merve Nur Tekin, Gülay Bilgin, Cansu Yılmaz Yeğit, Hanife Tuğçe Çağlar, Zeynep Seda Uyan, Fazılcan Zirek, Beste Özsezen, Berna Oğuz, Ayşe Tana Aslan, Sevgi Pekcan, Handan Kekeç, N. Emiralioğlu Ordukaya, Nilgün Kula, Hanife Büşra Küçük
article en

Abstract

<bold>Introduction:</bold> Despite the great impact of PIBO on children, clinical data is scarce, and most clinicians need more awareness of the disease. We aimed to evaluate patients' demographic, clinical, radiologic findings with PIBO in the Childhood Interstitial Lung Diseases Registry of Türkiye(chILD-TR). <bold>Materials and Methods:</bold> The current age, gender, symptoms, systemic diseases, physical examination, laboratory and radiological findings, therapies of patients with PIBO in the chILD-TR database were recorded in 2022-2023. <bold>Results:</bold> There were 180 patients, 61.1% were male. The current age of the patients was 103.23(13-364), the age at which symptoms started was 25.96(0-233.1), the age at hospital admission was 48.65(0-303.9) months.56.1% of the patients had a history of recurrent lower respiratory tract infection, 17.8% of the patients had growth retardation. The most common symptom was cough(77.8%). Oxygen was used in 12.8% of the patients, noninvasive mechanical ventilator was used in 3.3%. The most common physical examination finding was rhonchi(61.7%). There was a mosaic perfusion pattern in all patients on thorax CT;other common findings were increased aeration(42.8%), thickening of the bronchial wall(41.1%). Mean FEV1, FVC, MEF25-75 values were 61.12±21.68%, 66.45±22.55%, 50.26±28.10%. The most common infection agent was adenovirus(17.2%). 32.2% of patients were using oral steroids. The follow-up period was 85.24±68.29 months. 2 of the patients died. <bold>Discussion:</bold> Physicians need better awareness of PIBO as patients were referred to a pediatric pulmonologist almost 2 years after symptom onset. Patient registries have an essential role in increasing awareness.

Ministry of Health (TR), Izmir University (TR), Ankara University (TR), Akdeniz University (TR), Bezmiâlem Vakıf Üniversitesi (TR), Ege University (TR), Gaziantep Children's Hospital (TR), Memorial Ankara Hospital (TR), Necmettin Erbakan University (TR), Istanbul University-Cerrahpaşa (TR), Istinye University (TR), Education Training And Research (US), Kayseri Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), Istanbul Medeniyet University (TR), Hacettepe University (TR), Istanbul University (TR), Marmara University (TR), University of Health Sciences Antigua (AG), Erciyes University (TR), Gazi University (TR)
Good health and well-being
Openalex Percentile: Top 63%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.