Comparison of Pneumonia Severity Index and CURB-65 Score with Laboratory Parameters in Predicting In-Hospital Mortality for Community Acquired Pneumonia

<bold>Objectives:</bold> We aimed to investigate the relationships of hematologic parameters with commonly used scores PSI, CURB-65 and qSOFA to predict the prognosis of patients hospitalized with community-acquired pneumonia(CAP). <bold>Methods:</bold> This study is a multicenter observational study. Patients with a diagnosis of pneumonia admitted to the chest diseases clinics were included the study. <bold>Results:</bold> The study included 163(47%) female with an average age of 74.4±11.8. Hospital mortality was detected in 51 patients. When comparing CAP patients who had a fatal outcome with those who survived, the group with a fatal outcome had higher age(p=0.007), CURB-65(p<0.001), PSI(p<0.001), qSOFA(p<0.001), length of hospital stay(p=0.001), and total antibiotic duration (p<0.001). The neutrophil/lymphocyte ratio(NLR)(p=0.009), monocyte/lymphocyte ratio (MLR) (p=0.018), and platelet/lymphocyte ratio(PLR (p=0.025) were higher in the group with a fatal outcome. When examining the correlation of NLR, MLR, and PLR with clinical scoring systems, it was found that NLR was positively correlated with CURB-65, PSI, and qSOFA, PLR was correlated with PSI and qSOFA, and MLR was correlated with CURB-65. <bold>Conclusion:</bold> NLR, PLR, and MLR are elevated at the time of diagnosis in patients who succumb to CAP. Additionally, NLR and MLR exhibit good correlation with CURB-65, while NLR and PLR show good correlation with PSI.