Monitorization Of Pulmonary Nodules In Turkey (MONITUR)

<bold>Introduction:</bold> Pulmonary nodules are lesions within the lung parenchyma, surrounded by normal lung tissue. It is important to distinguish malignant nodules from other nodules at an early stage. This study aims to provide a national data on pulmonary nodule patients. <bold>Methods:</bold> This is a multicenter, retrospective study.1316 patients from 30 centers, between 01.01.2014 and 31.12.2019, who had at least two thorax computed tomographies (CT) during follow-up or who had a single CT with a histopathological diagnosis, were included. <bold>Results:</bold> Of the 1316 patients, %39.9 were female, and the average age was 57.63 years. The average follow-up period was 20.21 months. The average diameter value varied between 8.6 and 14 mm. The most common location for nodules was the right lung and peripheral location. It was determined that PET/CT examination was requested in %30.9 (407) of the patients with pathological FDG uptake in pulmonary nodules were %51.1. Age, male gender and smoking were associated with malignancy. Irregular, lobulated, spicular edges and cavitary features were detected at higher rates in malignant nodules. The rate of stable nodules was %68 (873), the rate of progression was %10.4 (131). CT diameter was detected as a risk factor for malignancy (p<0.001). When the cut-off value for the first CT diameter was 10 mm, the sensitivity was found to be %88.2, the specificity was %76.08, the PPV was %55.04 and the NPV value was %95.1. <bold>Conclusions:</bold> Our study provides information on guideline compliance in the management of incidental pulmonary nodules and may help create national approaches and algorithms.

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Published
2024-09-14
DOI
https://doi.org/10.1183/13993003.congress-2024.pa5255
Primary Topic
Lung Cancer Diagnosis and Treatment
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article
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article

Monitorization Of Pulmonary Nodules In Turkey (MONITUR)

Sibel Kara, Fatih Üzer, Şeyma Başlılar, Belma Akbaba Bağcı et al.
Lung Cancer Diagnosis and Treatment
article

Monitorization Of Pulmonary Nodules In Turkey (MONITUR)

Sibel Kara, Fatih Üzer, Şeyma Başlılar, Belma Akbaba Bağcı, Hülya Dirol, Elif Yelda Özgün Niksarlıoğlu, Berna Kömürcüoğlu, Ahmet Ilgazlı, Derya Yeni̇berti̇z, Süha Alzafer, Dilek Ergün, Ahmet Cemal Pazarlı, Serap Argun Barış, Abidin Şehitoğulları, Utku Tapan, Hıdır Eşme, Nimet Aksel, Ahmet Arısoy, Nurhan Sarıoğlu, Sibel Arınç, Ahmet Bircan, Neslihan Özçelik, Bahar Kurt, Aydanur Ekici, A. Taskin, Muharrem Erol, Tevfik Özlü, Hadice Selimoğlu Şen, M. Group, Şule Çi̇lekar, Betül Aksu, Günhan Yavasoglu
article en

Abstract

<bold>Introduction:</bold> Pulmonary nodules are lesions within the lung parenchyma, surrounded by normal lung tissue. It is important to distinguish malignant nodules from other nodules at an early stage. This study aims to provide a national data on pulmonary nodule patients. <bold>Methods:</bold> This is a multicenter, retrospective study.1316 patients from 30 centers, between 01.01.2014 and 31.12.2019, who had at least two thorax computed tomographies (CT) during follow-up or who had a single CT with a histopathological diagnosis, were included. <bold>Results:</bold> Of the 1316 patients, %39.9 were female, and the average age was 57.63 years. The average follow-up period was 20.21 months. The average diameter value varied between 8.6 and 14 mm. The most common location for nodules was the right lung and peripheral location. It was determined that PET/CT examination was requested in %30.9 (407) of the patients with pathological FDG uptake in pulmonary nodules were %51.1. Age, male gender and smoking were associated with malignancy. Irregular, lobulated, spicular edges and cavitary features were detected at higher rates in malignant nodules. The rate of stable nodules was %68 (873), the rate of progression was %10.4 (131). CT diameter was detected as a risk factor for malignancy (p<0.001). When the cut-off value for the first CT diameter was 10 mm, the sensitivity was found to be %88.2, the specificity was %76.08, the PPV was %55.04 and the NPV value was %95.1. <bold>Conclusions:</bold> Our study provides information on guideline compliance in the management of incidental pulmonary nodules and may help create national approaches and algorithms.

Sakarya University (TR), Van Yüzüncü Yıl Üniversitesi (TR), Ministry of Health (TR), Izmir University (TR), Selçuk University (TR), Recep Tayyip Erdoğan University (TR), Karadeniz Technical University (TR), Süleyman Demirel Üniversitesi (TR), Başkent University (TR), Bursa Technical University (TR), Akdeniz University (TR), Usak University (TR), Tokat Gaziosmanpaşa Üniversitesi (TR), Haliç University (TR), Konya Food and Agriculture University (TR), Yıldız Technical University (TR), Npistanbul Brain Hospital (TR), Chest Diseases Hospital (KW), Sivas State Hospital (TR), Ankara Spine Center (TR), Education Training And Research (US), Atos (Turkey) (TR), Haydarpaşa Numune Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), Yedikule Teaching Hospital (TR), Afyonkarahisar Sağlık Bilimleri Üniversitesi, Kocaeli Üniversitesi (TR), Afyon Kocatepe University (TR), Muğla University (TR), Kastamonu University (TR)
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