Harnessing the potential of zinc oxide nanoparticles and their derivatives as nanofertilizers: Trends and perspectives

The agriculture sector is currently facing a decline in plant productivity and yield. Different technologies are being developed to combat these risks. However, innovation in existing technologies is required. Nanotechnology has the potential to solve these difficulties by modifying traditional farming practices and approaches. Nanoparticles (NPs) can bind and transport various substances, such as plant nutrients, and govern their slow release over a longer period, which can reduce the danger of nutrient losses while maintaining environmental safety. In this aspect, the role of zinc oxide nanoparticles (ZnO NPs) and their derivatives in agriculture has recently sparked a lot of interest. ZnO NPs can be coated with different compounds which enhance their biocompatibility within the plant cells. The unique nanostructures and nano-characteristics of ZnO NPs and their derivatives have resulted in the development of a novel approach for boosting plant development and productivity as well as improved stress tolerance via targeted delivery and slow-release mechanism, resulting in enhanced nutrient use efficiency, regulating phytohormone levels, enhancing root morphology, and increasing enzyme activity, leading to their application as nanofertilizers. There are important knowledge gaps regarding the long-term environmental consequences and the specific biochemical pathways influenced by ZnO NPs. This review aims to provide an overview of the most recent advancements in the use of ZnO NPs in agriculture, identify areas where more research is needed, and suggest potential future research directions. • Zinc oxide nanoparticles play a remarkable role as nanofertilizers. • Zinc oxide nanoparticles applied under in vitro, in vivo , and field conditions significantly alter plant biology. • Coating zinc oxide nanoparticles with other molecules enhances their capability.