Can a single basal cistern urokinase bolus help to prevent subarachnoid hemorrhage consequences?
Single bolus cisternal 100,000UI urokinase administration during emergency aneurysm clipping reduces vasospasm, mortality, and the need for permanent CSF diversion. It is not associated with a significant increase in intracranial hemorrhages or systemic fibrinolysis.
Authors
- Vicente Vanaclocha (ORCID: https://orcid.org/0000-0002-4909-5886)
- Juan José Dosta Herrera
- Leyre Vanaclocha (ORCID: https://orcid.org/0000-0002-7215-2105)
- Marlon Rivera-Paz (ORCID: https://orcid.org/0000-0002-6224-5156)
- Nieves Sáiz‐Sapena (ORCID: https://orcid.org/0000-0001-7816-3617)
Institutions
- Universitat de València (ES)
- Valencia Catholic University Saint Vincent Martyr (ES)
- Hospital General Universitario De Valencia (ES)
Publication Details
- Journal
- Heliyon
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e40080
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00