An integrative lipidomics and transcriptomics study revealing Bavachin and Icariin synergistically induce idiosyncratic liver injury
<b>Conslusions:</b> Collectively, these results suggest that alterations in intracellular metabolism and gene expression levels may contribute to the synergistic induction of IDILI by the incompatible pair Bav and Ica in the presence of TNF-α.
Authors
- Xiaohe Xiao (ORCID: https://orcid.org/0000-0002-2836-2738)
- Bo Cao (ORCID: https://orcid.org/0000-0003-4623-7348)
- Shuya Qi
- Guohui Li (ORCID: https://orcid.org/0000-0002-1739-4048)
- Chunyu Li (ORCID: https://orcid.org/0000-0002-5767-5127)
- Yingying Li (ORCID: https://orcid.org/0000-0003-1184-9475)
- Jiabo Wang (ORCID: https://orcid.org/0000-0001-8070-9543)
- Jing Xu
- Mengmeng Lin
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Chinese PLA General Hospital (CN)
- National Clinical Research (US)
- Chinese People's Liberation Army (CN)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1080/08923973.2024.2424293
- Citations
- 4
- Primary Topic
- Medicinal Plant Pharmacodynamics Research
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China