Oral epithelial dysplasia with lichenoid features shares proteomic overlap with oral epithelial dysplasia without lymphocytic immune response

The proteomic profile of OEDwithLF is similar to OED without associated lymphocytic infiltration, but significantly different from LM. OED is relevant in lichenoid tissues, and its proteomic changes can be detected. Although OED may coexist with interface mucositis, it is not a defining feature of LM. This challenges the exclusion of epithelial dysplasia from lichenoid diagnoses. Based on this hypothesis-generating study, further investigation is warranted.

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Publication Details

Journal
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology
Published
2024-11-07
DOI
https://doi.org/10.1016/j.oooo.2024.10.085
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Oral epithelial dysplasia with lichenoid features shares proteomic overlap with oral epithelial dysplasia without lymphocytic immune response

Cintia M. Chamorro‐Petronacci, Mário Pérez‐Sayáns, Pilar Gándara Vila, Andrés Blanco Carrión et al.
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology
Oral Health Pathology and Treatment
article

Oral epithelial dysplasia with lichenoid features shares proteomic overlap with oral epithelial dysplasia without lymphocytic immune response

Cintia M. Chamorro‐Petronacci, Mário Pérez‐Sayáns, Pilar Gándara Vila, Andrés Blanco Carrión, Susana B. Bravo, Martina Coppini, Vito Carlo Alberto Caponio, Eliana Melissa Perez-Garcia, Alejandro I. Lorenzo-Pouso, María Elena Padín-Iruegas, Fábio França-Vieira-E-Silva, Irene Lafuente-Ibañez-de-Mendoza
article en

Abstract

The proteomic profile of OEDwithLF is similar to OED without associated lymphocytic infiltration, but significantly different from LM. OED is relevant in lichenoid tissues, and its proteomic changes can be detected. Although OED may coexist with interface mucositis, it is not a defining feature of LM. This challenges the exclusion of epithelial dysplasia from lichenoid diagnoses. Based on this hypothesis-generating study, further investigation is warranted.

Oral Surgery Oral Medicine Oral Pathology and Oral RadiologyVol. 139(3)
University of Foggia (IT)
Universidade de Santiago de Compostela
Zero hunger
Openalex Percentile: Top 77%
Oral Health Pathology and Treatment
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