Tetrahedral framework nucleic acids inhibit Aβ-mediated ferroptosis and ameliorate cognitive and synaptic impairments in Alzheimer’s disease
Collectively, tFNAs inhibited Aβ-mediated ferroptosis and ameliorated cognitive and synaptic impairments in AD mice. tFNAs may serve as novel option to deal with AD.
Authors
- Lu Tan (ORCID: https://orcid.org/0000-0002-6685-0468)
- Chuangxin Liao (ORCID: https://orcid.org/0000-0002-5264-9739)
- Jiazhao Xie
- Xiong Wang (ORCID: https://orcid.org/0000-0002-4588-1898)
- Xiaoguang Li (ORCID: https://orcid.org/0000-0002-1726-696X)
- Liming Cheng
- Weiyun Zhang (ORCID: https://orcid.org/0000-0001-8075-9356)
- Changchun Cai
Institutions
- Union Hospital (HK)
- Wuhan Children's Hospital (CN)
- Central Hospital of Wuhan (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1186/s12951-024-02963-x
- Citations
- 14
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 5.87
Funders
- National Natural Science Foundation of China