Tumor prevalence in a cohort of ambulatory COPD patients.

<bold>Introduction and methodology:</bold> A retrospective descriptive database study of patients diagnosed with COPD according to GOLD criteria with follow-up in a monographic consultation of the Hospital Virgen Macarena from January 1, 2012 to October 31, 2023 was performed. <bold>Results:</bold> A total of 772 patients (651 men and 123 women) were analyzed. The mean age was 64 years. According to the GOLD scale 10.4% presented mild severity, 30.2% moderate, 33.8% severe and 25.4% very severe. Some type of tumor was present in 25.5% (197) of the series. The most frequent cancer diagnosed was lung cancer (35%, 69 patients) with the epidermoid subtype predominating with 20% (40), followed by adenocarcinoma and microcytic cancer (78% and 3%), respectively. Other tumors with high prevalence were colorectal, with 17.7% (35), basal cell carcinoma with 9.6% (19), followed by bladder and prostate, representing 8.1% each (16) Patients not diagnosed with tumor had an FEV1 of 45.69 % (SD 17.62) with 372 (SD 129.59) meters in the T6MM, a score of 4 (SD 2) on the BODE scale, dyspnea 2 (SD 1) on the mMRC scale, in addition to a pack-year index (PAI) of 53.1 (SD 27.8), a Charlson index of 3 (SD 2) and a corresponding overweight BMI (27.71, SD 6.24). Patients diagnosed with any tumor had similar pulmonary function, dyspnea and severity as patients without tumors, but were more comorbid with a Charlson of 5 (SD 3, p=0.01)) and obese, with a BMI of 34.41 (SD 72.55, p=0.035). <bold>Conclusion:</bold> -There is a significant prevalence of tumors among patients with COPD, especially those of pulmonary and colorectal origin. -This condition is related to a greater smoking burden, obesity and a higher Charlson index score.