Extra pulmonary treatable traits in a paediatric problematic severe asthma (PSA) population

<bold>Background:</bold> Pulmonary, extra-pulmonary and psychological treatable traits have been identified in an adult asthma population (1). Children and young people (CYP) referred to our PSA service have treatable traits identified during a multidisciplinary nurse-led assessment. <bold>Objectives:</bold> Determine prevalence and nature of treatable extra pulmonary traits in CYP with PSA referred to a tertiary centre. <bold>Methods:</bold> A retrospective review of CYP with PSA referrals between 2013 – 2023. Extra pulmonary treatable traits were identified prospectively as atopic disorders (rhinitis eczema and food allergies), overweight (BMI ≥25), gastro-oesophageal reflux, , and breathing pattern disorders. <bold>Results:</bold> 427 CYP median (range) age 11.7 (5.1 – 17.6) years, 57% male, were assessed. Hay fever was the most common extrapulmonary trait (77.9%) and other atopic disorders were also very common (Table 1). 22.2% of children were overweight or obese. <fig><object-id>erj;64/suppl_68/PA1331/F1</object-id><object-id>F1</object-id><object-id>F1</object-id><graphic></graphic></fig> <bold>Conclusion:</bold> Extra-pulmonary treatable traits are common in CYP with PSA. It is important to identify these to tailor a holistic approach to management. 1. Agusti A, Bel E, Thomas M, et al. Treatable traits: toward precision medicine of chronic airway diseases. Eur Respir J. 2016;47:410‐419.