Embryo movement is required for limb tendon maturation
We conclude that specific aspects of tendon maturation require controlled levels of dynamic muscle-generated stimulation. Such a developmental approach to understanding how tendons are constructed will inform future work to engineer improved tensile load-bearing tissues.
Authors
- Nicholas Dunne (ORCID: https://orcid.org/0000-0003-4649-2410)
- Paula Murphy (ORCID: https://orcid.org/0000-0002-8048-6850)
- Rebecca A. Rolfe (ORCID: https://orcid.org/0000-0003-2177-3136)
- Niamh E. Buckley (ORCID: https://orcid.org/0000-0001-9326-8513)
- Spencer E. Szczesny (ORCID: https://orcid.org/0000-0002-7691-949X)
- Helen O. McCarthy (ORCID: https://orcid.org/0000-0002-1254-3745)
- Ebru Talak Bastürkmen
- Lauren Sliney (ORCID: https://orcid.org/0000-0003-3178-8278)
- Grace Hayden
Institutions
- University College Dublin (IE)
- Queen's University Belfast (GB)
- Pennsylvania State University (US)
- Trinity College Dublin (IE)
- Advanced Materials and BioEngineering Research (IE)
- I-Form Advanced Manufacturing Research Centre (IE)
- Dublin City University (IE)
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-11-04
- DOI
- https://doi.org/10.3389/fcell.2024.1466872
- Citations
- 5
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.39
Funders
- National Science Foundation
- Science Foundation Ireland
- Trinity College Dublin