Representing ECM composition and EMT pathways in gastric cancer using a new metastatic gene signature
This gene signature may help identify stage I GC patients at higher risk, offering potential utility in early-stage patient management. Furthermore, our experimental ECM model may serve as a platform for investigating molecular mechanisms underlying metastatic spread in gastric cancer.
Authors
- Alessandro Sgambato (ORCID: https://orcid.org/0000-0002-9487-4563)
- Pellegrino Mazzone (ORCID: https://orcid.org/0000-0002-6217-1505)
- Pietro Zoppoli (ORCID: https://orcid.org/0000-0002-7860-9655)
- Mario De Felice (ORCID: https://orcid.org/0000-0003-0009-8725)
- Giovanni Calice (ORCID: https://orcid.org/0000-0002-2545-1401)
- Elena Amendola (ORCID: https://orcid.org/0000-0001-5545-3048)
- Orazio Ignomirelli
- Giuseppina Di Paola
- F. Albano (ORCID: https://orcid.org/0000-0001-6157-7688)
- Sabino Russi (ORCID: https://orcid.org/0000-0002-4467-4942)
- Simona Laurino (ORCID: https://orcid.org/0000-0002-5220-3227)
- Rocco Galasso (ORCID: https://orcid.org/0000-0003-4831-6437)
- Chiara Balzamo
- Geppino Falco (ORCID: https://orcid.org/0000-0001-6193-7233)
- Mario Ciuffi
- Ottavia Bartolo
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Centro di Riferimento Oncologico della Basilicata (IT)
- Biogem (IT)
- Federico II University Hospital (IT)
- Institute for Experimental Endocrinology and Oncology (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-11-05
- DOI
- https://doi.org/10.3389/fcell.2024.1481818
- Citations
- 4
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 1.13
Funders
- Ministero della Salute