Liver metastasized pancreatic neuroendocrine tumor in a 17‐year‐old female: A case report

Neuroendocrine tumors (NETs) are rare tumors in adults and extremely rare in the pediatric population, as pancreatic NETs (pNETs) have an incidence rate of <0.1 per million. We present a case of a 17-year-old female with a liver metastasized pNET. A 17-year-old female with a history of intermittent abdomen-back pain presented to the clinic with severe upper abdominal pain radiating to the shoulder. The routine tests were normal. An ultrasound showed multiple lesions in the liver, which were confirmed by a computed tomography (CT) that uncovered a pancreatic lesion too. A liver biopsy proved it was a metastasized pNET with positive NET markers on IMC staining. The metaiodobenzylguanidine (MIBG) scan flared the liver lesion. The patient was started on Octreotide long-acting release (LAR) 30 mg once monthly. The rarity of these tumors makes their diagnosis difficult, but they should not be omitted and must be considered when there are long-lasting symptoms that are not compatible with common illnesses. These tumors are curable in their early stages.

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Publication Details

Journal
Clinical Case Reports
Published
2024-11-01
DOI
https://doi.org/10.1002/ccr3.9545
Citations
1
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
Field-Weighted Citation Impact
0.39
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article

Liver metastasized pancreatic neuroendocrine tumor in a 17‐year‐old female: A case report

Muhammad Umair Sultan, Nisreen Khazem
1 citations
Clinical Case Reports
Neuroendocrine Tumor Research Advances
0.39
article

Liver metastasized pancreatic neuroendocrine tumor in a 17‐year‐old female: A case report

Muhammad Umair Sultan, Nisreen Khazem
article en
1 citations

Abstract

Neuroendocrine tumors (NETs) are rare tumors in adults and extremely rare in the pediatric population, as pancreatic NETs (pNETs) have an incidence rate of <0.1 per million. We present a case of a 17-year-old female with a liver metastasized pNET. A 17-year-old female with a history of intermittent abdomen-back pain presented to the clinic with severe upper abdominal pain radiating to the shoulder. The routine tests were normal. An ultrasound showed multiple lesions in the liver, which were confirmed by a computed tomography (CT) that uncovered a pancreatic lesion too. A liver biopsy proved it was a metastasized pNET with positive NET markers on IMC staining. The metaiodobenzylguanidine (MIBG) scan flared the liver lesion. The patient was started on Octreotide long-acting release (LAR) 30 mg once monthly. The rarity of these tumors makes their diagnosis difficult, but they should not be omitted and must be considered when there are long-lasting symptoms that are not compatible with common illnesses. These tumors are curable in their early stages.

Clinical Case ReportsVol. 12(11)
Damascus University (SY)
Good health and well-being
Openalex Percentile: Top 32%
Neuroendocrine Tumor Research Advances
0.39
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