Epigenetic modification of Igf2/H19 imprinting control region regulates PGC-1α/PI3K/AKT2 pathway in a rat model of intrauterine growth restriction
The methylation status and histone modification in the IGF2/H19 ICR are related to growth and lipid metabolism via the PGC-1α/PI3K/AKT2 pathway in IUGR rats.
Authors
- Yaqin Yan
- W.A. Long (ORCID: https://orcid.org/0000-0002-8267-5858)
- Xiaoping Luo (ORCID: https://orcid.org/0000-0002-3748-4817)
- Meihui Zhang (ORCID: https://orcid.org/0000-0002-0752-9877)
- Zhou Xiu-yun
- Lihong Liao (ORCID: https://orcid.org/0000-0002-4405-4516)
- Tulian Lin
- Qin Ning (ORCID: https://orcid.org/0000-0002-0741-7111)
Institutions
- Wuhan University (CN)
- Zhengzhou University (CN)
- Guangzhou Women and Children Medical Center (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Henan Provincial People's Hospital (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Chinese Medical Journal
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1097/cm9.0000000000003324
- Citations
- 2
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China