Carrier Frequency and Incidence of <i>MUTYH</i>-Associated Polyposis Based on Database Analysis in East Asians and Koreans
This was the first study to investigate the frequency of carriers of <i>MUTYH</i>-associated polyposis in East Asians, including specific subgroups, utilizing gnomAD and a Korean genome database. Our data provide valuable reference information for future investigations of <i>MUTYH</i>-associated polyposis to understand the genetic diversity and specific variants associated with this condition in East Asian populations.
Authors
- Mi‐Ae Jang (ORCID: https://orcid.org/0000-0002-6558-5236)
- Dongju Won (ORCID: https://orcid.org/0000-0002-0084-0216)
- Boyoung Park (ORCID: https://orcid.org/0000-0003-1902-3184)
- Chang‐Seok Ki (ORCID: https://orcid.org/0000-0001-7679-8731)
- Sun‐Young Kong (ORCID: https://orcid.org/0000-0003-0620-4058)
- Jong Eun Park (ORCID: https://orcid.org/0000-0001-9131-6518)
- Eun Hye Cho (ORCID: https://orcid.org/0000-0002-9328-9389)
- Taeheon Lee (ORCID: https://orcid.org/0000-0001-5650-3094)
Institutions
- Yonsei University (KR)
- Samsung Medical Center (KR)
- Genome and Company (South Korea) (KR)
- Kangbuk Samsung Hospital (KR)
- National Cancer Center (KR)
- Hanyang University Guri Hospital (KR)
- Hanyang University (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Annals of Laboratory Medicine
- Published
- 2024-11-05
- DOI
- https://doi.org/10.3343/alm.2024.0242
- Citations
- 3
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- Ministry of Education
- Ministry of Health and Welfare
- National Cancer Center
- National Research Foundation of Korea