Irisin Attenuates Hepatic Stellate Cell Activation and Liver Fibrosis in Bile Duct Ligation Mice Model and Improves Mitochondrial Dysfunction
Irisin effectively attenuated HSC activation, ameliorated liver fibrosis in BDL mice, and improved associated mitochondrial dysfunction. These findings highlight the therapeutic potential of irisin for the treatment of liver fibrosis.
Authors
- Jeana Hong (ORCID: https://orcid.org/0000-0003-0332-7466)
- Seung‐Soon Im (ORCID: https://orcid.org/0000-0002-2743-2108)
- Dae Hee Choi (ORCID: https://orcid.org/0000-0002-8956-7518)
- Seon Mee Kang (ORCID: https://orcid.org/0000-0002-4056-7525)
- Giang Nguyen (ORCID: https://orcid.org/0000-0001-5156-4904)
- Eun-Hee Cho (ORCID: https://orcid.org/0000-0002-1349-8894)
- Jae‐Ho Lee (ORCID: https://orcid.org/0000-0002-5562-0720)
- So Young Park (ORCID: https://orcid.org/0000-0003-1518-2516)
- Tin Pou Lai
- Phuc Nguyen Huu Pham
Institutions
- Kangwon National University (KR)
- Keimyung University (KR)
Publication Details
- Journal
- Endocrinology and Metabolism
- Published
- 2024-11-05
- DOI
- https://doi.org/10.3803/enm.2024.1984
- Citations
- 9
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Kangwon National University