A Rare Case of Solitary Cardiac Myofibroma in an Infant

Solitary myofibromas are rare, benign, mesenchymal tumors typically found in the head and neck regions. We report an exceptionally rare case of a solitary cardiac myofibroma and its short-term management and outcome. A two-month-old infant was referred due to a murmur. Echocardiography revealed a 2 × 1 cm solitary mass originating from a mitral papillary muscle, causing severe regurgitation. Magnetic resonance imaging showed the mass to be homogeneous on T1, hyperintense on T2, and hypointense on first-pass perfusion imaging with no enhancement on delayed postcontrast imaging. The mass was surgically excised partially due to its involvement with the mitral valve. Postoperative recovery was uneventful, with echocardiography four months later showing no tumor recurrence and trivial mitral regurgitation. This report provides valuable imaging and pathology examples to aid in the recognition of this rare tumor and demonstrates that successful surgical excision is possible, even with significant cardiac involvement.

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Publication Details

Journal
World Journal for Pediatric and Congenital Heart Surgery
Published
2024-11-04
DOI
https://doi.org/10.1177/21501351241286453
Citations
1
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
0.40
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article

A Rare Case of Solitary Cardiac Myofibroma in an Infant

Elizabeth H. Stephens, Joseph J. Maleszewski, Rebecca Ameduri, Joseph A. Dearani et al.
1 citations
World Journal for Pediatric and Congenital Heart Surgery
Cardiac tumors and thrombi
0.40
article

A Rare Case of Solitary Cardiac Myofibroma in an Infant

Elizabeth H. Stephens, Joseph J. Maleszewski, Rebecca Ameduri, Joseph A. Dearani, M. Yasir Qureshi, Patrick O’Leary, Liwei Yu
article en
1 citations

Abstract

Solitary myofibromas are rare, benign, mesenchymal tumors typically found in the head and neck regions. We report an exceptionally rare case of a solitary cardiac myofibroma and its short-term management and outcome. A two-month-old infant was referred due to a murmur. Echocardiography revealed a 2 × 1 cm solitary mass originating from a mitral papillary muscle, causing severe regurgitation. Magnetic resonance imaging showed the mass to be homogeneous on T1, hyperintense on T2, and hypointense on first-pass perfusion imaging with no enhancement on delayed postcontrast imaging. The mass was surgically excised partially due to its involvement with the mitral valve. Postoperative recovery was uneventful, with echocardiography four months later showing no tumor recurrence and trivial mitral regurgitation. This report provides valuable imaging and pathology examples to aid in the recognition of this rare tumor and demonstrates that successful surgical excision is possible, even with significant cardiac involvement.

World Journal for Pediatric and Congenital Heart SurgeryVol. 16(1)
Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Good health and well-being
Openalex Percentile: Top 31%
Cardiac tumors and thrombi
0.40
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A Rare Case of Solitary Cardiac Myofibroma in an Infant — Elizabeth H. Stephens, Joseph J. Maleszewski, et al. · World Journal for Pediatric and Congenital Heart Surgery (2024) | TGRS Research Map | TGRS