Comparative Analytical Study of Intravitreal Triamcinolone Acetonide Versus Bevacizumab in Managing Diabetic Macular Edema: Insights From a Tertiary Eye Care Facility in India

Both IVTA and IVB effectively enhance visual acuity and reduce macular edema in diabetic retinopathy. IVB demonstrates superior short-term gains in visual acuity (over one to three months). In contrast, IVTA is more effective in decreasing CFT, thanks to its broader mechanism of action, including inhibition of vascular endothelial growth factor and cytokines. The longer half-life of IVTA provides more sustained anatomical benefits but is associated with higher IOP, necessitating careful monitoring. Conversely, IVB presents fewer complications, making it a safer option for certain patients. Treatment choice should consider the patient's risk profile, balancing efficacy with potential side effects.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2024-11-04
DOI
https://doi.org/10.7759/cureus.73022
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Comparative Analytical Study of Intravitreal Triamcinolone Acetonide Versus Bevacizumab in Managing Diabetic Macular Edema: Insights From a Tertiary Eye Care Facility in India

M Rajamohan, Harikrishnan Marappan, A. M. Raja
Cureus
Retinal Diseases and Treatments
article

Comparative Analytical Study of Intravitreal Triamcinolone Acetonide Versus Bevacizumab in Managing Diabetic Macular Edema: Insights From a Tertiary Eye Care Facility in India

M Rajamohan, Harikrishnan Marappan, A. M. Raja
article en

Abstract

Both IVTA and IVB effectively enhance visual acuity and reduce macular edema in diabetic retinopathy. IVB demonstrates superior short-term gains in visual acuity (over one to three months). In contrast, IVTA is more effective in decreasing CFT, thanks to its broader mechanism of action, including inhibition of vascular endothelial growth factor and cytokines. The longer half-life of IVTA provides more sustained anatomical benefits but is associated with higher IOP, necessitating careful monitoring. Conversely, IVB presents fewer complications, making it a safer option for certain patients. Treatment choice should consider the patient's risk profile, balancing efficacy with potential side effects.

CureusVol. 16(11)
Madurai Medical College (IN), Joseph Eye Hospital (IN), Institute of Medical Sciences (IN)
Openalex Percentile: Top 67%
Retinal Diseases and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.