Study of the hematological parameters in chronic kidney disease patients in a tertiary care centre

Background: Chronic kidney disease involves variety of distinct pathophysiological mechanisms, abnormal kidney function, and a progressive decline in glomerular filtration rate (GFR). Globally, chronic kidney disease is becoming a more serious public health issue. It is a newly recognized health issue that significantly raises the morbidity and death rates from non-communicable diseases. Methods: A cross sectional study was carried out in Laboratory of Pathology Department, B.J Medical College, Civil Hospital, and Ahmedabad over a period of 1.5 years January 2023 to July 2024. Two hundred patients of chronic kidney disease above 15 years of age, satisfying the inclusion and exclusion criteria, were included in the study. Results: The aim of the present study is to study various changes in hematological parameters that occur in the chronic kidney disease patients. Conclusion: The analysis of hematological parameters in patients with chronic kidney disease provides crucial insights into the disease's impact on various physiological functions. The study revealed significant deviations from normal levels across several key parameters. The study highlights the prevalence of anemia, reduced RBC count, and decreased hematocrit in chronic kidney disease patients, with a significant number showing normocytic normochromic anemia. These findings emphasize the critical role of regular and comprehensive hematological monitoring for Effective clinical management and to mitigate the progression of chronic kidney disease and improve patient outcomes.