Assessment of immune biomarkers during the transition period in Ongole cattle

The present study investigates the physiological responses, and gene expression of anti-inflammatory cytokines in transitional Ongole cows, a dual-purpose indigenous breed from Andhra Pradesh, India. Livestock significantly contributes to India's economy and understanding stress responses during the critical transition period from late pregnancy to early lactation is essential. The study measured respiratory rate, pulse rate, rectal temperature and the relative mRNA expression of IL10 in peripheral blood mononuclear cells (PBMCs) using the 2-ΔΔCq method. The results revealed significant changes in the parameters studied, providing insights into the stress adaptation mechanisms of Ongole cows during the transition period.