HOXC12 promotes the invasion and migration of gastric cancer cells by upregulating SALL4 and activating Wnt/β-catenin signaling pathway
HOXC12 promotes the invasion/migration of gastric cancer cells via SALL4/Wnt/β-catenin axis, and is negatively correlated with the infiltration of CD8<sup>+</sup> T cells, suggesting HOXC12 as a diagnostic marker and a potential therapeutic target for gastric cancer.
Authors
- Ming Lu (ORCID: https://orcid.org/0000-0003-3667-4915)
- Niuniu Hou (ORCID: https://orcid.org/0000-0002-2200-9300)
- Qian Chen (ORCID: https://orcid.org/0000-0001-6481-5776)
- Jing Zhang (ORCID: https://orcid.org/0000-0001-8861-7336)
- D. Sudhaker Rao
- Zhongliang Ning
Institutions
- University of Science and Technology of China (CN)
- Anhui Medical University (CN)
- Anhui Provincial Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1007/s12672-024-01502-2
- Citations
- 5
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 1.17