Pharmacological inhibition of KSper impairs flagellar pH homeostasis of human spermatozoa
Our results demonstrate that hKSper inhibition evokes flagellar pH<sub>i</sub> acidification of human spermatozoa, suggesting that flagellar pH<sub>i</sub> maintenance is an important signaling mechanism of hKSper on the regulation of sperm functions.
Authors
- Xuhui Zeng (ORCID: https://orcid.org/0000-0002-5936-4699)
- Hang Kang
- Nanxi Ji
- Xiaorong Wang (ORCID: https://orcid.org/0000-0002-9488-733X)
Institutions
- Nantong University (CN)
- Nantong Maternity and Child Health Hospital (CN)
Publication Details
- Journal
- Andrology
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1111/andr.13796
- Citations
- 1
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province