Quantifying Mast Cell and Eosinophil Cellular Density in Skin Biopsy Tissue From Adults With Maculopapular Cutaneous Mastocytosis as Compared With Urticaria and Normal Skin: A Retrospective Histopathologic Study
This study adds to the literature by providing objective mast cell density data to distinguish challenging cases of cutaneous mastocytosis from urticarial reactions and normal skin. Future studies could explore the development of computer-aided estimations of cellular density with more extensive comparison with other inflammatory conditions to translate our findings more readily into clinical practice.
Authors
- Anne L. King
- Austin W. Todd (ORCID: https://orcid.org/0000-0002-6115-4770)
- Julia Scott Lehman (ORCID: https://orcid.org/0000-0002-7389-3853)
- Carilyn N. Wieland (ORCID: https://orcid.org/0000-0002-7706-370X)
- Emma F. Johnson (ORCID: https://orcid.org/0000-0003-3962-1771)
- Carmen M. Montagnon (ORCID: https://orcid.org/0000-0001-8150-2317)
- Shruti Agrawal (ORCID: https://orcid.org/0000-0003-0123-432X)
Institutions
- Mayo Clinic (US)
- WinnMed (US)
- Mayo Clinic in Arizona (US)
- Vanderbilt Health (US)
Publication Details
- Journal
- American Journal of Dermatopathology
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1097/dad.0000000000002878
- Citations
- 1
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.24