Cu(I)‐Catalyzed Silylation and Germylation of Azauracils
The current study demonstrates a Cu(I) catalyzed direct C(sp<sup>2</sup>)-H silylation and germylation of azauracil using triphenylsilane and triphenylgermane. A broad scope, excellent functional group tolerance, and suitability for large-scale reactions are exhibited in this protocol. Moreover, this method can be readily applied to structurally complex bioactive molecules. Experimental results suggest a radical mechanistic pathway for the reaction.
Authors
- Asim Kumar Ghosh (ORCID: https://orcid.org/0000-0002-4493-525X)
- Alakananda Hajra (ORCID: https://orcid.org/0000-0001-6141-0343)
- Frenki Mahato
Institutions
- Visva-Bharati University (IN)
Publication Details
- Journal
- Chemistry - A European Journal
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1002/chem.202403685
- Citations
- 7
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- Human Resource Development Group