PCN‐134(Fe)‐Gated Organic Photoelectrochemical Transistor with Unique Dual‐Directional Signaling

Abstract Recently, increasing attention has been paid to exploring the unique characteristics of newly emerged organic photoelectrochemical transistors (OPECT) for biological application and neuromorphic engineering due to their effectiveness for light‐driven ionic regulation of channels interfaced with rich biochemical reactions. The observation of interesting signaling reversion is reported—the realization of dual‐directional signaling with enhanced signal resolution—enabled by porous coordination networks (PCN)‐134(Fe) in the presence of varying H 2 O 2 concentrations, which is totally different from exiting unidirectional signaling in OPECT. The underlying mechanism of such behavior is attributed to the change in the polarity of the gate photocurrent and is explained from the perspective of potential distribution. The practical application of this device is then studied by detecting the phorbol myristate acetate (PMA)‐induced secretion of H 2 O 2 from three kinds of human breast cells. This study features the realization of dual‐directional signaling, which is expected to catalyze a new category of OPECT operation with unknown possibilities.