Emergence of Carbapenem-Resistant Uropathogenic Escherichia coli (ST405 and ST167) Strains Carrying blaCTX-M-15, blaNDM-5 and Diverse Virulence Factors in Hospitalized Patients
This study provides insights into the molecular epidemiology of carbapenem-resistant Uropathogenic <i>E. coli</i> (Carb-R UPEC) strains and highlights the presence of globally high-risk <i>E. coli</i> clones exhibiting extensive drug resistance phenotypes in Pakistani hospitals. The findings underscore the urgent need for enhanced surveillance and stringent antibiotic stewardship to manage the spread of these highly resistant and virulent strains within hospital settings.
Authors
- Mohsin Khurshid (ORCID: https://orcid.org/0000-0002-3196-2857)
- Muhammad Hidayat Rasool (ORCID: https://orcid.org/0000-0002-6324-1798)
- Bilal Aslam (ORCID: https://orcid.org/0000-0002-5568-5049)
- Muhammad Shafiq (ORCID: https://orcid.org/0000-0002-4346-5903)
- Fatima Mujahid
Institutions
- Government College University, Faisalabad (PK)
- Shantou University (CN)
- Shantou University Medical College (CN)
Publication Details
- Journal
- Pathogens
- Published
- 2024-11-05
- DOI
- https://doi.org/10.3390/pathogens13110964
- Citations
- 14
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 2.38