Intracardiac Sarcoma Arising From Metastasis of a Primary Phyllodes Tumor of the Breast

A 57-year-old woman with a malignant phyllodes tumor of the breast and recent bilateral pulmonary emboli presented with an incidental intracardiac mass on transthoracic echocardiography. Because of concern for clot burden aspiration, thrombectomy was performed. Pathology findings were consistent with spindle-cell sarcoma and histologically similar to the malignant phyllodes breast tumor. Current treatment strategies for this condition include chemotherapy and surgery. Aspiration thrombectomy typically is performed for retrieval of venous thromboemboli; however, our case suggests the procedure may be another diagnostic and therapeutic option for malignant cardiac tumors.

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Publication Details

Journal
Annals of Internal Medicine Clinical Cases
Published
2024-11-01
DOI
https://doi.org/10.7326/aimcc.2023.1267
Primary Topic
Cardiac tumors and thrombi
Type
article
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article

Intracardiac Sarcoma Arising From Metastasis of a Primary Phyllodes Tumor of the Breast

Jori E. May, Kara F. Morton, Stephen Clarkson, Vanessa Eulo et al.
Annals of Internal Medicine Clinical Cases
Cardiac tumors and thrombi
article

Intracardiac Sarcoma Arising From Metastasis of a Primary Phyllodes Tumor of the Breast

Jori E. May, Kara F. Morton, Stephen Clarkson, Vanessa Eulo, Silvio Litovsky, Mustafa I. Ahmed, Donovon Allen
article en

Abstract

A 57-year-old woman with a malignant phyllodes tumor of the breast and recent bilateral pulmonary emboli presented with an incidental intracardiac mass on transthoracic echocardiography. Because of concern for clot burden aspiration, thrombectomy was performed. Pathology findings were consistent with spindle-cell sarcoma and histologically similar to the malignant phyllodes breast tumor. Current treatment strategies for this condition include chemotherapy and surgery. Aspiration thrombectomy typically is performed for retrieval of venous thromboemboli; however, our case suggests the procedure may be another diagnostic and therapeutic option for malignant cardiac tumors.

Annals of Internal Medicine Clinical CasesVol. 3(11)
University of Alabama at Birmingham (US)
Openalex Percentile: Top 64%
Cardiac tumors and thrombi
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Intracardiac Sarcoma Arising From Metastasis of a Primary Phyllodes Tumor of the Breast — Jori E. May, Kara F. Morton, et al. · Annals of Internal Medicine Clinical Cases (2024) | TGRS Research Map | TGRS