Therapeutic drug monitoring of tenofovir disoproxil and emtricitabine in oral HIV pre-exposure prophylaxis (PrEP) users who have undergone gastrointestinal surgery
Plasma trough concentrations of TFV observed in our cohort taking TDF/FTC were above the expected concentrations associated with PrEP efficacy as previously described in the literature, suggesting that PrEP can be safely given in this population, with TDM used for reassurance.
Authors
- Victoria Tittle
- Marta Boffito (ORCID: https://orcid.org/0000-0002-2213-1103)
- Shema Tariq (ORCID: https://orcid.org/0000-0001-9802-7727)
- Nicolò Girometti (ORCID: https://orcid.org/0000-0002-2960-2748)
- Olamide Dosekun
- Harry Coleman (ORCID: https://orcid.org/0000-0002-1935-2407)
- Stephanie Tyler
- Rachael Jones
- Yee Suh Teh (ORCID: https://orcid.org/0000-0001-5663-4932)
- Muhammad Ismail (ORCID: https://orcid.org/0000-0002-1450-2568)
- Erica Pool (ORCID: https://orcid.org/0000-0001-8086-7285)
- Anna Nakamura
- Hannah Loftus
- Katrina Stegmann
Institutions
- University College London Hospitals NHS Foundation Trust (GB)
- Imperial College Healthcare NHS Trust (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Chelsea and Westminster Hospital NHS Foundation Trust (GB)
- Royal Berkshire Hospital (GB)
- Central London Community Healthcare NHS Trust (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- Mortimer Market Centre (GB)
- University College London (GB)
Publication Details
- Journal
- International Journal of STD & AIDS
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1177/09564624241298983
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.00