The role of lncRNA TSIX in osteoarthritis pathogenesis: mechanistic insights and clinical biomarker potential
This study demonstrated an increased expression of TSIX in OA patients. It suggests that TSIX may play a role in chondrocyte dysfunction during OA by modulating the miR-320a/PTEN axis.
Authors
- Xiu-Quan Guo
- Ganggang Wang (ORCID: https://orcid.org/0000-0001-5388-0847)
- Liubing Dong (ORCID: https://orcid.org/0000-0002-1787-8595)
- Junhui Xie
- Futao Ji
Institutions
- Shanghai Jiao Tong University (CN)
- Zhengzhou City Hospital (CN)
- Zoucheng People's Hospital (CN)
- Shanghai Children's Hospital (CN)
- Shenzhen Pingle Orthopedic Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1186/s13018-024-05207-8
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- Shanghai Jiao Tong University
- Sanming Project of Medicine in Shenzhen