Osmotic demyelination syndrome: revisiting the diagnostic criteria through two fatal cases
ODS traditionally carried a poor prognosis, with high mortality rates and diagnoses often made postmortem. However, recent advances in understanding the pathophysiology, along with improvements in diagnostic techniques such as MRI and intensive care treatments, have led to earlier identification, treatment, and recognition of milder forms of the syndrome. Despite these advancements, ODS remains a critical condition with significant risks, particularly following the rapid correction of severe hyponatremia.
Authors
- Martina Padovano (ORCID: https://orcid.org/0000-0003-2452-7926)
- Alessandro Santurro (ORCID: https://orcid.org/0000-0001-5491-3719)
- Matteo Scopetti (ORCID: https://orcid.org/0000-0002-7259-3090)
- Vittorio Fineschi (ORCID: https://orcid.org/0000-0002-1686-3236)
- Francesca Consalvo
- Giuseppe Delogu (ORCID: https://orcid.org/0000-0002-6128-9835)
- Donato Morena (ORCID: https://orcid.org/0000-0001-6473-7632)
- Biancamaria Treves
Institutions
- University of Salerno (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- BMC Neurology
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1186/s12883-024-03934-3
- Citations
- 12
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.61