Anti-inflammatory effects of eupatilin on Helicobacter pylori CagA-induced gastric inflammation
Eupatilin treatment demonstrated anti-inflammatory effects on CagA-positive H. pylori-infected gastric epithelial cells by inhibiting CagA translocation, thereby suppressing the NF-κB signaling pathway. These results suggest that eupatilin plays a protective role against CagA-positive H. pylori-induced gastritis.
Authors
- Bong Eun Lee (ORCID: https://orcid.org/0000-0003-2734-2134)
- Gwang Ha Kim (ORCID: https://orcid.org/0000-0001-9721-5734)
- Moon Won Lee (ORCID: https://orcid.org/0000-0002-8411-6398)
- Dong Chan Joo
- Su Jin Park (ORCID: https://orcid.org/0000-0001-8313-7640)
Institutions
- Pusan National University Hospital (KR)
- Pusan National University (KR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1371/journal.pone.0313251
- Citations
- 10
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 5.73
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea