Fatal Borealpox in an Immunosuppressed Patient Treated With Antivirals and Vaccinia Immunoglobulin—Alaska, 2023
This report demonstrates that BRPV can cause overwhelming disseminated infection in certain immunocompromised patients. Based on the patient's initial response, early BRPV identification and antiviral therapies might have been beneficial. These therapies, in combination with optimized immune function, should be considered for patients at risk for manifestations of BRPV.
Authors
- Julia H. Rogers (ORCID: https://orcid.org/0000-0003-3516-7276)
- Li Yu
- Alexandra Tuttle (ORCID: https://orcid.org/0000-0001-8202-9402)
- Julian A. Villalba (ORCID: https://orcid.org/0000-0001-9230-8747)
- Joseph B McLaughlin (ORCID: https://orcid.org/0009-0002-7818-7226)
- Agam K. Rao (ORCID: https://orcid.org/0000-0002-7231-555X)
- Andrea M. McCollum (ORCID: https://orcid.org/0000-0002-9136-818X)
- John Laurance
- Louisa J. Castrodale
- Benjamin Westley
- Sarah Y. Park (ORCID: https://orcid.org/0000-0002-5997-2723)
- Sivan Bercovici (ORCID: https://orcid.org/0000-0002-4310-4868)
- Kimberly Wilkins
- Shivkumar Venkatasubrahmanyam
- Jayme Parker (ORCID: https://orcid.org/0000-0003-2040-2923)
- Sarah Reagan-Steiner
- Jeffrey B. Doty (ORCID: https://orcid.org/0000-0001-5713-9685)
- Michael B. Townsend (ORCID: https://orcid.org/0000-0002-0354-7437)
- Christina L. Hutson (ORCID: https://orcid.org/0000-0001-7998-9728)
- Panayampalli S. Satheshkumar (ORCID: https://orcid.org/0000-0003-1472-1418)
- K. David Newell (ORCID: https://orcid.org/0000-0003-2303-9242)
- Jiusheng Deng (ORCID: https://orcid.org/0000-0003-1758-3778)
- Nicholas Noll (ORCID: https://orcid.org/0000-0003-1698-7500)
- William Carson (ORCID: https://orcid.org/0000-0001-7188-8674)
- Whitni Davidson (ORCID: https://orcid.org/0000-0003-3372-7903)
- Crystal M. Gigante
- Julu Bhatnagar
- Lisa Smith
- Thomas Mego
Institutions
- Centers for Disease Control and Prevention (US)
- Providence Alaska Medical Center (US)
- Alaska Department of Health and Social Services (US)
- Centers for Disease Control and Prevention (UG)
- Epidemic Intelligence Service (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1093/cid/ciae536
- Citations
- 5
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 1.47