TCF4 promotes apoptosis and Wnt/β-catenin signaling pathway in acute kidney injury via transcriptional regulation of COX7A2L
The study revealed the pivotal role of COX7A2L in AKI, which is regulated by TCF4 and modulates the Wnt/β-catenin signaling pathway, highlighting its potential as a therapeutic target.
Authors
- Minhui Xi
- Hualin Qi
- Jingyuan Lu
Institutions
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1371/journal.pone.0307667
- Citations
- 1
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.23