Structural Elucidation and Complete NMR Spectral Assignments of <i>Monascus</i> Monacolin Analogs
One new monacolin analog, monacolin V (1), together with two new monacolin-like natural products, 6-hydroxyl monacolin P (2) and 3-keto monacolin S (3), were isolated from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were identified by HRESIMS and NMR experiments, and the complete assignments of <sup>1</sup>H and <sup>13</sup>C NMR data for three compounds were obtained by the aid of HSQC, HMBC, <sup>1</sup>H-<sup>1</sup>H COSY, and NOESY data. This is the first time that the NMR data of compounds 2 and 3 have been fully assigned.
Authors
- Ronghua Pan
- Qingjiang Xu
- Xiao-Ya Shang (ORCID: https://orcid.org/0000-0003-2193-1712)
- Xin Wang (ORCID: https://orcid.org/0000-0001-5920-1745)
- Nan Wang (ORCID: https://orcid.org/0000-0003-4630-5216)
- Yonghong Zhang (ORCID: https://orcid.org/0000-0001-9565-7563)
- Jiachen Liu (ORCID: https://orcid.org/0000-0002-0263-3704)
- Lizhong Zheng (ORCID: https://orcid.org/0000-0002-6108-0222)
Institutions
- Beijing Union University (CN)
- Zhejiang Ocean University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Magnetic Resonance in Chemistry
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1002/mrc.5489
- Primary Topic
- Microbial Metabolism and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00