Prolonged sitafloxacin and doxycycline combination regimen for treating infections by highly resistant <i>Mycoplasma genitalium</i>
Prolonged combination therapy is highly effective against M. genitalium strains with concurrent parC and gyrA mutations. Future research should focus on establishing the optimal treatment duration and monitoring the risk of resistance.
Authors
- Hiroaki Kubota (ORCID: https://orcid.org/0000-0002-6339-8568)
- Daisuke Mizushima (ORCID: https://orcid.org/0000-0001-8424-4616)
- Hiroyuki Gatanaga (ORCID: https://orcid.org/0000-0001-9191-9984)
- Morika Mitobe (ORCID: https://orcid.org/0000-0002-1466-7661)
- Naokatsu Ando (ORCID: https://orcid.org/0000-0002-5520-2780)
- Kenji Sadamasu (ORCID: https://orcid.org/0000-0003-0541-706X)
- Shinichi Oka (ORCID: https://orcid.org/0000-0002-9283-2167)
- Kôji Watanabe (ORCID: https://orcid.org/0000-0002-3190-8439)
- Misao Takano (ORCID: https://orcid.org/0000-0001-5059-110X)
- Takahiro Aoki (ORCID: https://orcid.org/0009-0002-4451-599X)
- Jun Suzuki (ORCID: https://orcid.org/0009-0006-2322-9176)
- Hirofumi Miyake (ORCID: https://orcid.org/0000-0003-3629-5333)
- Kai Kobayashi (ORCID: https://orcid.org/0000-0003-4524-284X)
Institutions
- National Center for Global Health and Medicine (JP)
- Tokyo Metropolitan Institute of Public Health (JP)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1093/jac/dkae403
- Citations
- 5
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- National Center for Global Health and Medicine