Cdc42 improve SARS-CoV-2 spike protein-induced cellular senescence through activating of Wnt/β-Catenin signaling pathway
This study provides insights into the mechanisms underlying cellular senescence induced by the SARS-CoV-2 spike protein, offering potential strategies to mitigate the inflammatory response and complications associated with COVID-19 in both the acute and long-term phases.
Authors
- Wei Xü (ORCID: https://orcid.org/0000-0002-3135-5010)
- Guodong Hu (ORCID: https://orcid.org/0000-0001-6770-0667)
- Lihan Shen (ORCID: https://orcid.org/0000-0002-6632-6885)
- Linyi Luo
- Yaoqin Yuan
- Zhenhua Wu (ORCID: https://orcid.org/0000-0003-4552-883X)
- Chan Yang (ORCID: https://orcid.org/0009-0009-8848-1710)
- Yinghua Chen (ORCID: https://orcid.org/0000-0003-2295-7228)
- Jianping Zhou (ORCID: https://orcid.org/0000-0001-8687-7222)
- Chunmei Nong
Institutions
- Dongguan People’s Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2024-11-04
- DOI
- https://doi.org/10.3389/fcimb.2024.1449423
- Citations
- 3
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.98