<scp>FoxO1</scp> Deficiency in Monocytic Myeloid‐Derived Suppressor Cells Exacerbates B Cell Dysfunction in Systemic Lupus Erythematosus
Our findings indicate that effective inhibition of B cells mediated by the ALKBH5/FoxO1/Met axis in M-MDSCs could offer a novel therapeutic approach to manage SLE.
Authors
- Huan Dou (ORCID: https://orcid.org/0000-0001-6330-398X)
- Wei Kong (ORCID: https://orcid.org/0000-0001-6720-6810)
- Kangxing Zhou
- Yayi Hou (ORCID: https://orcid.org/0000-0002-1152-9132)
- Jun Liang (ORCID: https://orcid.org/0000-0001-5536-6569)
- Liping Tan (ORCID: https://orcid.org/0000-0002-1773-0435)
- Shuangan Wang
Institutions
- China Pharmaceutical University (CN)
- Nanjing Drum Tower Hospital (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1002/art.43046
- Citations
- 6
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.44
Funders
- Nanjing University