Enhancing the science in the Global transmission of Nipah virus

Since the Nipah virus's discovery two decades ago, a great deal of knowledge has been applied to the virus's genome, pathology, and wide selectivity of transmission. The highly lethal zoonotic paramyxovirus known as the Nipah virus was first identified in Malaysia in 1998. It's a pathogen that is intimate enough to cause encephalitis caused by the current respiratory virus. The key to controlling discharge is the proactive diagnosis and use of virus management techniques. Only a small number of the 14 bat species found in Malaysia have been identified as vectors of viral transmission, affecting humans, horses, cats, dogs, and pigs. The review provides an explanation of the recent NIV outbreaks in the Philippines, Malaysia, Singapore, Bangladesh, and India. The method of transmission, the preventative and control measures used, and the available evidence following the outbreaks. The virus can also inadvertently result in large financial losses for farmers by seriously sickening animals like pigs. Additionally, it can spread from person to person. Non-invasive ventilation (NIV) is seen in the bronchiole epithelial cells during the early stages of human collapse. The anti-NIV specific IgM was found using the fastest ELISA assay, while the IgG antibody was found using an incidental IgG ELISA. These findings highlight the role that viral glycoproteins play in eliciting neutralizing antibodies, which act as potential vaccines to protect against the illness. Furthermore, there's a chance that these vaccinations will provide cross-protection against similarly related viruses.

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Publication Details

Journal
Asian Journal of Pharmaceutical Research
Published
2024-09-20
DOI
https://doi.org/10.52711/2231-5691.2024.00046
Primary Topic
Virology and Viral Diseases
Type
article
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article

Enhancing the science in the Global transmission of Nipah virus

Mahendra Jagtap, Prerana T. Borade, Sayali V. Bodake, Avinash B. Darekar
Asian Journal of Pharmaceutical Research
Virology and Viral Diseases
article

Enhancing the science in the Global transmission of Nipah virus

Mahendra Jagtap, Prerana T. Borade, Sayali V. Bodake, Avinash B. Darekar
article en

Abstract

Since the Nipah virus's discovery two decades ago, a great deal of knowledge has been applied to the virus's genome, pathology, and wide selectivity of transmission. The highly lethal zoonotic paramyxovirus known as the Nipah virus was first identified in Malaysia in 1998. It's a pathogen that is intimate enough to cause encephalitis caused by the current respiratory virus. The key to controlling discharge is the proactive diagnosis and use of virus management techniques. Only a small number of the 14 bat species found in Malaysia have been identified as vectors of viral transmission, affecting humans, horses, cats, dogs, and pigs. The review provides an explanation of the recent NIV outbreaks in the Philippines, Malaysia, Singapore, Bangladesh, and India. The method of transmission, the preventative and control measures used, and the available evidence following the outbreaks. The virus can also inadvertently result in large financial losses for farmers by seriously sickening animals like pigs. Additionally, it can spread from person to person. Non-invasive ventilation (NIV) is seen in the bronchiole epithelial cells during the early stages of human collapse. The anti-NIV specific IgM was found using the fastest ELISA assay, while the IgG antibody was found using an incidental IgG ELISA. These findings highlight the role that viral glycoproteins play in eliciting neutralizing antibodies, which act as potential vaccines to protect against the illness. Furthermore, there's a chance that these vaccinations will provide cross-protection against similarly related viruses.

Asian Journal of Pharmaceutical Research
Shri Vile Parle Kelavani Mandal (IN)
Openalex Percentile: Top 70%
Virology and Viral Diseases
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Enhancing the science in the Global transmission of Nipah virus — Mahendra Jagtap, Prerana T. Borade, et al. · Asian Journal of Pharmaceutical Research (2024) | TGRS Research Map | TGRS