IDENTIFICATION OF ANTIDIABETIC COMPOUNDS IN AN ANTIDIABETIC RECIPE USED IN TRADITIONAL CONGOLESE MEDICINE

The recipes of plants used in traditional medicine, prepared by traditional practitioners and preserved in unpalatable conditions of medicines, are in the majority void of scientific information. In order to highlight the phytochemical composition of antidiabetic drugs used in traditional congolese medicine, chemical analyses were carried out on one of the beverages called NGOSI, purchased from Congolese traditional therapists. The results obtained showed the predominance of polyphenols, sugars, flavonoids and triterpene glycosides in this recipe. 48 compounds were observed in this recipe, including 26 compounds identified by CG/MS, 10 suggested compounds identified by HPLC/MS and 12 non-identity compounds according to the databases used. Some compounds present in this recipe, such as scopoletin, which is proven to be antidiabetic, and vanillin, recognized as an antioxidant capable of significantly reducing serum glucose and triglyceride levels and increasing insulin levels, would justify the antidiabetic activity of this recipe and its traditional use by the congolese population.