Causal Effects of Gastroesophageal Reflux on Chronic Rhinosinusitis: A Bidirectional Two‐Sample Mendelian Randomization Study
This MR analysis revealed that genetically predicted GER had a causal effect on an increased risk of CRS or CR, but not vice versa. These results have great implications for the management of CRS (especially for refractory CRS) or CR in clinical practice.
Authors
- Hongbing Yao (ORCID: https://orcid.org/0000-0002-9177-1251)
- Yang Yang (ORCID: https://orcid.org/0000-0002-3681-5856)
- Li Xuelei
- Liang Jia (ORCID: https://orcid.org/0009-0001-7752-8538)
- Xin Xiang (ORCID: https://orcid.org/0000-0003-2133-2373)
- Tang Xinye
Institutions
- China International Science and Technology Cooperation (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Clinical Otolaryngology
- Published
- 2024-11-03
- DOI
- https://doi.org/10.1111/coa.14251
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00